Structure of lomatin, a new coumarin

✍ Scribed by Taito O. Soine; Fuad H. Jawad

• Book ID: 102401966
• Publisher: John Wiley and Sons
• Year: 1964
• Tongue: English
• Weight: 151 KB
• Volume: 53
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600530845

✦ Synopsis

Exa rr... iation c the coumarin content of the petroleum ether extract of Lomatium rrutbllii (A. Gray) has revealed that the principal component is a compound, m.p. 187-188O, [a]gO + 74.8' (EtOH), corresponding to the formula ClaH:r04. We have named this substance lomutin, and our structural studies indicate that it is (+)-3'-hydroxy-3',4'-dihydroseselin (I). Infrared spectral (Nujol mull) show principal absorption frequencies a t 3500 (free OH), 1700 (C=O), 1600 and 1487 (aromatic C=C), 1281 and 10'75 em.-' (OH deformation and C-0 stretching). Ultraviolet spectra show 246 mp (loge 3.78), 257 (3.56), and 329 (4.11);