STRUCTURE OF HUMAN RENIN AND EXPRESSION OF THE RENIN GENE
β Scribed by Brian J. Morris; Daniel F. Catanzaro; Judy Hardman; Nikola Mesterovic; Judy Tellam; Yvonne Hort; Bruce H. Bennetts; John Shine
- Book ID
- 108933227
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 277 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0305-1870
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π SIMILAR VOLUMES
## Abstract The regulation of __renin__ gene expression, the rateβlimiting enzyme of the system, is thought to be fundamental to the total system. Previously, we mapped six putative __cis__βelements in the promoter region of the human __renin__ gene with nuclear proteins from human chorionic cells
Most patients with nephroblastoma have high levels of plasma renin and some are hypertensive. Blood pressure falls after removal of the affected kidney, suggesting that nephroblastoma is associated with renin production either by the tumour or by the kidney. In this study, direct evidence was sought