A STRUCTURAL ANALYSIS OF HUMAN RENIN
β Scribed by Brian J. Morris; J. Mitchell Guss; William N. Hunter; Daniel F. Catanzaro
- Book ID
- 108934336
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 351 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0305-1870
No coin nor oath required. For personal study only.
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Light scattering has been used to investigate the structure of human tracheobronchial mucin glycoproteins (HTBM) from the sputum of cystic fibrosis patients. The specimen was extracted using 6M guanidinium hydrochloride solution and fractionated by gel exclusion chromatography on Sephacryl S-1OOO. T
Although essential arterial hypertension is believed to have a strong genetic predisposition, the gene(s) responsible are unknown. The mechanisms underlying the regulation of blood pressure and experimental studies place the renin gene among the main candidate genes that need to be tested in humans.