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Structure of exo,exo-2,3-endo,endo-5,6-tetrabromobicycloheptane

✍ Scribed by Tuncer Hökelek; Osman Çakmak; Ahmet Tutar


Book ID
110410535
Publisher
Springer
Year
1998
Tongue
English
Weight
306 KB
Volume
28
Category
Article
ISSN
1572-8854

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A convenient, high-yield synthesis of N-Boc-7-azabicyclo[2.2.1]hept-5-en-2-one (7) was developed by SmI 2 -mediated desulfonylation of 6. Thus, 5-endo-, 5-exo-, 6-endo-, and 6-exo-hydroxylated epibatidine analogues 2a,b and 3a,b were synthesized from 7 by using a Pd(PPh 3 ) 4 -catalyzed reductive He