Structure of (dimethyl sulfoxide-S){glyoxylic acid thiosemicarbazonato(2–)-O,N,S }platinum(II)

✍ Scribed by N. I. Dodoff; D. Kovala-Demertzi; J. Kuduk-Jaworska; M. Kubiak; A. Kochel

• Book ID: 102121779
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 171 KB
• Volume: 42
• Category: Article
• ISSN: 0232-1300
• DOI: 10.1002/crat.200610858

✦ Synopsis

Abstract

A crystal of the title complex [Pt(DMSO)(GT)] (1a), where H~2~GT = glyoxylic acid thiosemicarbazone, has been characterized by X‐ray crystallography and its structure has been compared with that of the recently described cytotoxic complex [Pt(DMSO)(GT)]·DMSO (1). The crystal of 1a is monoclinic; space group P 2~1~/n; unit cell dimensions: a = 7.3270(10), b = 10.313(2), c = 13.706(3) Å, β = 101.92(3)°; V = 1013.3(3) Å^3^; Z = 4. The Pt(II) ion is approximately planar tetragonal coordinated by the carboxylato oxygen, azomethine nitrogen and thiolato sulfur atom of the doubly deprotonated H~2~GT molecule, and the sulfur atom of DMSO. The two five membered chelate rings are almost coplanar. In distinct with 1, the sulfoxide oxygen atom and thiolato sulfur atom are in gauche position. A system of hydrogen bonds of the type N–H···O involving the amino, carboxylato and sulfoxide groups links the complex molecules within the unit cells. The π ‐π stacking pattern between the chelate rings in 1a involves centrosymmetric pairs of complex molecules and differs from that in 1. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)