Structure of a tetracyclic intermediate in the synthesis of Daphniphyllum alkaloids
✍ Scribed by Castellano, E. E. ;Brocksom, T. J. ;Ceschi, M. A.
- Book ID
- 114510459
- Publisher
- International Union of Crystallography
- Year
- 1994
- Tongue
- English
- Weight
- 280 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0108-2701
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## Abstract An efficient method for the synthesis of 4‐aminotetrahydrocarbazole derivatives from 2,3‐dihydrospiro‐[1__H__‐carbazole‐1,2′‐(1,3)‐dithiolan]‐4‐(9__H__)‐one 1 is described. The structure of compound 6 has been confirmed by X‐ray structure analysis.
In 1909, Yagl (2) isolated from the bark of DaDhDiDiKflh8 ucromdum HIgael (Euphorbiaoeae) an aurphoua alhaloid, daphnluarlne, C2$4104h, up. 75-two.
Daphnilactone B1 was a major component of the alkaloids, isolated from the fruits of Daphniphyllum macropodum Miquel. This alkaloid has never been isolated from other parts of this plant. The spectral data' of daphnilactone B showed the presence of a secondary methyl group ( 6 l.OOppm, 31-1, d, J=bH