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Intermediates for the synthesis of tetracyclic indole alkaloids. Synthesis of 4-aminotetrahydrocarbazole derivatives

✍ Scribed by Süleyman Patir; Görol Okay; Ahmet Gülce; Bekir Salih; Tuncer Hökelek


Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
299 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

An efficient method for the synthesis of 4‐aminotetrahydrocarbazole derivatives from 2,3‐dihydrospiro‐[1__H__‐carbazole‐1,2′‐(1,3)‐dithiolan]‐4‐(9__H__)‐one 1 is described. The structure of compound 6 has been confirmed by X‐ray structure analysis.


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Aldehyde Intermediates in the Synthesis
✍ Arto Tolvanen; David Din Belle; Mauri Lounasmaa 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 German ⚖ 394 KB

## Abstract The synthesis of aldehyde intermediates suitable for the preparation of indole alkaloids of the tacamine (1) type is described. The four possible aldehydes 4–7 were prepared from methyl 5‐ethylnicotinate (8) in a few simple steps using a base‐catalyzed epimerization as the final step (_