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Structure of 5-methyl-2'-deoxycytidine 5'-monophosphate dihydrate

โœ Scribed by Lalitha, H. N. ;Ramakumar, S. ;Viswamitra, M. A.


Book ID
114506584
Publisher
International Union of Crystallography
Year
1989
Tongue
English
Weight
438 KB
Volume
45
Category
Article
ISSN
0108-2701

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An enzymatic method has been developed to synthesize S-methyldeoxycytidine triphosphate (m'dCTP) starting with dCMP and formaldehyde as substrates. Methylation is catalyzed by a dCMP methyltransferase in the presence of tetrahydrofolic acid. The resulting m'dCMP is converted to m'dCTP by a kinase pr