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Structure determination of the anorexic agent mazindol

โœ Scribed by Sandor Barcza; William J. Houlihan


Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
277 KB
Volume
64
Category
Article
ISSN
0022-3549

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Mazindol, 5-(p-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, has been shown to be an effective anorexic. To explore the structure-activity relationships, several 1-ethyl-3-substituted-4-aryl-4-hydroxyindeno[1,2-c]pyrazoles were prepared and subjected to various animal screens. The 1-ethy

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