Permethylation of the glycan isolated from the glycoinositol phospholipid (GPI) anchor of the scrapie prion protein (PrPSc) trimethylates a free hexosamine to form a quarternary ammonium salt, substantially increasing the sensitivity for analysis by mass spectrometry. This derivatization induces spe
Structure determination of glycoinositol phospholipid anchors by permethylation and tandem mass spectrometry
โ Scribed by BALDWIN, M; STAHL, N; BURLINGAME, A; PRUSINER, S
- Book ID
- 123412997
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 682 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1046-2023
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