Structure cristalline du 5H-pyrazolo[3,4-d]pyrimidine thione-4
✍ Scribed by Gadret, M. ;Goursolle, M. ;Leger, J. M.
- Book ID
- 117858958
- Publisher
- International Union of Crystallography
- Year
- 1974
- Weight
- 385 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0567-7408
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The molecular structure of the protonated form of tisopurine, 4-thioxo-2,5H,7H '-pyrazolo [ 3,4-d ] pyrimidinium chloride, (TPH'Cl-), was determined by x-ray di †raction methods. The crystals are monoclinic, C 5 H 5 N 4 SCl space group with a = 7.332(5), b = 10.911(9) and c = 9.423(8) b = 104.99(6)Ä
## Abstract Pyrazolo‐[3,4‐__d__]pyrimidine‐4,6‐diones **5** and pyrazolo[4,3‐__d__]pyrimidine‐5,7‐diones **7** were synthesized by Curtius rearrangement of pyrazolic mono‐esters **2** and **3** followed by hetero‐cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.