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Structure-Based Prediction of Potential Binding and Nonbinding Peptides to HIV-1 Protease

✍ Scribed by Kurt, Nese; Haliloglu, Turkan; Schiffer, Celia A.


Book ID
118515278
Publisher
Biophysical Society
Year
2003
Tongue
English
Weight
290 KB
Volume
85
Category
Article
ISSN
0006-3495

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## Abstract The constants of binding of five peptide analogs to the active site of the HIV‐1 aspartic‐protease are calculated based on a novel sampling scheme that is efficient and does not introduce any approximations in addition to the energy function used to describe the system. The results agre