✦ LIBER ✦

Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors

✍ Scribed by Hauel, Norbert H.; Nar, Herbert; Priepke, Henning; Ries, Uwe; Stassen, Jean-Marie; Wienen, Wolfgang

Book ID: 111880271
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 300 KB
Volume: 45
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0109513

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design of Novel, Nonpeptidic Thrombin In

Design of Novel, Nonpeptidic Thrombin Inhibitors and Structure of a Thrombin–Inhibitor Complex

✍ Dipl.-Chem. Ulrike Obst; Dr. Volker Gramlich; Prof. François Diederich; Dr. Lutz 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 478 KB 👁 1 views

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel Nonpeptidic Thrombin Inhibitors.

✍ Ulrike Obst; Patrick Betschmann; Christian Lerner; Paul Seiler; Francois Diederi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Structure-Based Design of Nonpeptidic Th

Structure-Based Design of Nonpeptidic Thrombin Inhibitors: Exploring the D-Pocket and the Oxyanion Hole

✍ Patrick Betschmann; Stefan Sahli; François Diederich; Ulrike Obst; Volker Gramli 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 493 KB 👁 2 views

Structure-activity relationships for new members of a class of nonpeptidic, low-molecular-weight inhibitors of thrombin, a key serine protease in the blood coagulation cascade, are described. These compounds, which originate from X-ray-structure-based design, feature a conformationally rigid, bi-or

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide- Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors.

✍ S. THAISRIVONGS; K. D. WATENPAUGH; W. J. HOWE; P. K. TOMICH; L. A. DOLAK; K.-T. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design and Synthesis of Novel Thrombin Inhibitors Based on Phosphinic Peptide Mimetics.

✍ Min Li; Zhaolan Lin; Michael E. Johnson 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design of Potent β-Lactamase Inhibitors

✍ K. Gubernator; I. Heinze-Krauss; P. Angehrn; R. L. Charnas; C. Hubschwerlen; C. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views