✦ LIBER ✦

Structure-Based Design of Highly Selective β-Secretase Inhibitors: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

✍ Scribed by Ghosh, Arun K.; Venkateswara Rao, Kalapala; Yadav, Navnath D.; Anderson, David D.; Gavande, Navnath; Huang, Xiangping; Terzyan, Simon; Tang, Jordan

Book ID: 115522482
Publisher: American Chemical Society
Year: 2012
Tongue: English
Weight: 513 KB
Volume: 55
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm3008823

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Potent Memapsin 2 (

ChemInform Abstract: Potent Memapsin 2 (β-Secretase) Inhibitors: Design, Synthesis, Protein-Ligand X-Ray Structure, and in vivo Evaluation.

✍ Arun K. Ghosh; et al. et al. 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 18 KB

Design, Synthesis and X-ray Structure of

Design, Synthesis and X-ray Structure of Protein−Ligand Complexes: Important Insight into Selectivity of Memapsin 2 (β-Secretase) Inhibitors

✍ Ghosh, Arun K.; Kumaragurubaran, Nagaswamy; Hong, Lin; Lei, Hui; Hussain, Khaja 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 81 KB

Structure-based design, synthesis and bi

Structure-based design, synthesis and biological evaluation of β-glucuronidase inhibitors

✍ Khan, Khalid M.; Ambreen, Nida; Taha, Muhammad; Halim, Sobia A.; Zaheer-ul-Haq, 📂 Article 📅 2014 🏛 Springer Netherlands 🌐 English ⚖ 650 KB

Design, Synthesis, and Crystal Structure

Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase †

✍ Maillard, Michel C.; Hom, Roy K.; Benson, Timothy E.; Moon, Joseph B.; Mamo, Shu 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 162 KB

Potent HIV-1 protease inhibitors incorpo

Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein–ligand X-ray studies

✍ Ghosh, Arun K.; Gemma, Sandra; Takayama, Jun; Baldridge, Abigail; Leshchenko-Yas 📂 Article 📅 2008 🏛 Royal Society of Chemistry 🌐 English ⚖ 376 KB

Structure-Based Design, Synthesis, and B

Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors

✍ Tao, Zhi-Fu; Wang, Le; Stewart, Kent D.; Chen, Zehan; Gu, Wendy; Bui, Mai-Ha; Me 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 463 KB