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Structure-Based Design of a New Bisintercalating Anthracycline Antibiotic

โœ Scribed by Chaires, Jonathan B.; Leng, Fenfei; Przewloka, Teresa; Fokt, Izabela; Ling, Yi-He; Perez-Soler, Roman; Priebe, Waldemar


Book ID
127202136
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
165 KB
Volume
40
Category
Article
ISSN
0022-2623

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The structure of a new antibiotic, roseophilin, was elucidated to be as shown iu Fig. 1 by NMR spectral analysis including a variety of two-dimensional techniques. Roseophilin was found to possess a novel skeleton containing pyrrole and furan moieties.