Structure and stereochemistry of 11-(o-chlorophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one hemiethanol solvate
✍ Scribed by Soriano-García, M. ;Cortés, E. ;Toscano, R. A. ;Arellano, M. del R. ;Martínez, R.
- Book ID
- 114504822
- Publisher
- International Union of Crystallography
- Year
- 1987
- Tongue
- English
- Weight
- 322 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0108-2701
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## Abstract A new synthesis to obtain eleven novel derivatives of 11‐[(__o__‐ __m__‐ and __p__‐substituted)‐phenyl]‐8‐chloro‐3,3‐dimethyl‐2,3,4,5,10,11‐hexahydro‐1__H__‐dibenzo[__b,e__][1,4]diazepin‐1‐ones with possible pharmacological activity in the central nervous system in two efficient steps h
## Abstract The preparation of twelve novel 2,3,4,5,10,11‐hexahydro‐1__H__‐dibenzo[__b__,__e__] [1,4]diazepin‐l‐ones which have potentially useful pharmacological properties; by condensation and cyclization between 3‐{[4‐(__o__‐; __m__‐; __p__‐methoxy)phenylthio]‐1,2‐phenylenediamine}‐5,5‐dimethyl‐