Structure and stability of proteins: The role of solvent
β Scribed by Joel Janin
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 489 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0166-6622
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π SIMILAR VOLUMES
Protein unfolding occurs when the balance of forces between the protein's interaction with itself and the protein's interaction with its environment is disrupted. The disruption of this balance of forces may be as simple as a perturbance of the normal water structure around the protein. A decrease i
## Synopsis Differential scanning microcalorimetry was used to investigate the enthalpy ( m d ) and the temperature ( t d ) of thermal denaturation of normal (nondeuterated) (H-PC) and deuterated (D-PC) phycocyanins in Dz0 solvent. Values of t d in D-PC are about 5-7Β°C lower than those in H-PC. Th
The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms. This was achieved by multiple mutations and often by ut