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Structure and Stability of an Immunoglobulin Superfamily Domain from Twitchin, a Muscle Protein of the NematodeCaenorhabditis elegans

✍ Scribed by Sun Fong; Stefan J. Hamill; Mark Proctor; Stefan M.V. Freund; Guy M. Benian; Cyrus Chothia; Mark Bycroft; Jane Clarke


Book ID
115627651
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
611 KB
Volume
264
Category
Article
ISSN
0022-2836

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Stability and peptide binding affinity o
✍ Wendell A. Lim; Robert O. Fox; Frederic M. Richards πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 569 KB

## Abstract We have determined the thermodynamic stability and peptide binding affinity of the carboxy‐terminal Src homology 3 (SH3) domain from the __Caenorhabditis elegans__ signal‐transduction protein Sem‐5. Despite its small size (62 residues) and lack of disulfide bonds, this domain is highly