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Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders

✍ Scribed by Maria V. Kim; Alexei S. Kasakov; Alim S. Seit-Nebi; Steven B. Marston; Nikolai B. Gusev


Book ID
116177671
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
388 KB
Volume
454
Category
Article
ISSN
0003-9861

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## Abstract The recently described human HSP22 belongs to the superfamily of small heat‐shock proteins containing a conservative α‐crystallin domain. HSP22 seems to be involved in regulation of cell proliferation, cardiac hypertrophy, apoptosis, and carcinogenesis, and expression of point mutants o