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Effect of mutations in the β5–β7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11)

✍ Scribed by Alexei S. Kasakov; Olesya V. Bukach; Alim S. Seit-Nebi; Steven B. Marston; Nikolai B. Gusev


Book ID
111312131
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
550 KB
Volume
274
Category
Article
ISSN
1432-1327

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## Abstract The recently described human HSP22 belongs to the superfamily of small heat‐shock proteins containing a conservative α‐crystallin domain. HSP22 seems to be involved in regulation of cell proliferation, cardiac hypertrophy, apoptosis, and carcinogenesis, and expression of point mutants o