𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure and Mechanism of MbtI, the Salicylate Synthase from Mycobacterium tuberculosis †

✍ Scribed by Zwahlen, Jacque; Kolappan, Subramaniapillai; Zhou, Rong; Kisker, Caroline; Tonge, Peter J.

Book ID
126843950
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
347 KB
Volume
46
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition Studies of Mycobacterium tube
Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)
✍ Alexandra Manos-Turvey; Esther M. M. Bulloch; Peter J. Rutledge; Edward N. Baker 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB

## Abstract Mycobacterium tuberculosis __salicylate synthase (MbtI), a member of the chorismate‐utilizing enzyme family, catalyses the first committed step in the biosynthesis of the siderophore mycobactin T. This complex secondary metabolite is essential for both virulence and survival of__ M. tub

Inhibitors of the Salicylate Synthase (M
Inhibitors of the Salicylate Synthase (MbtI) from Mycobacterium tuberculosis Discovered by High-Throughput Screening
✍ Dr. Mahalakshmi Vasan; Dr. João Neres; Jessica Williams; Daniel J. Wilson; Aaron 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 308 KB

## Abstract A simple steady‐state kinetic high‐throughput assay was developed for the salicylate synthase MbtI from __Mycobacterium tuberculosis__, which catalyzes the first committed step of mycobactin biosynthesis. The mycobactins are small‐molecule iron chelators produced by __M. tuberculosis__,