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Cover Picture: Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI) (ChemMedChem 7/2010)

✍ Scribed by Alexandra Manos-Turvey; Esther M. M. Bulloch; Peter J. Rutledge; Edward N. Baker; J. Shaun Lott; Richard J. Payne

Book ID: 102804393
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 930 KB
Volume: 5
Category: Article
ISSN: 1860-7179
DOI: 10.1002/cmdc.201090027

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Inhibition Studies of Mycobacterium tube

Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)

✍ Alexandra Manos-Turvey; Esther M. M. Bulloch; Peter J. Rutledge; Edward N. Baker 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB

## Abstract Mycobacterium tuberculosis __salicylate synthase (MbtI), a member of the chorismate‐utilizing enzyme family, catalyses the first committed step in the biosynthesis of the siderophore mycobactin T. This complex secondary metabolite is essential for both virulence and survival of__ M. tub