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Structure and ligand of a histone acetyltransferase bromodomain

โœ Scribed by Zhou, Ming-Ming; Dhalluin, Christophe; Carlson, Justin E.; Zeng, Lei; He, Cheng; Aggarwal, Aneel K.; Zhou, Ming-Ming

Book ID
109648114
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
616 KB
Volume
399
Category
Article
ISSN
0028-0836

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## Abstract Histone acetyltransferases (HATs) are a class of enzymes that participate in modulating chromatin structure and gene expression. Altered HAT activity has been implicated in a number of diseases, yet little is known about the regulation of HATs. In this study, we report that glycosaminog