Structure and function of histone acetyltransferases
β Scribed by R. Marmorstein
- Book ID
- 105740647
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 314 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1420-682X
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Acetylation of internal lysine residues of core histone N-terminal domains has been found correlatively associated with transcriptional activation in eukaryotes for more than three decades. Recent discoveries showing that several transcriptional regulators possess intrinsic histone acetyltransferase
## Abstract Histone acetyltransferases (HATs) are a class of enzymes that participate in modulating chromatin structure and gene expression. Altered HAT activity has been implicated in a number of diseases, yet little is known about the regulation of HATs. In this study, we report that glycosaminog