Structure and Function of the Androgen Receptor
✍ Scribed by OLLI A. JÄNNE; LI-XIN SHAN
- Book ID
- 119866500
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 708 KB
- Volume
- 626
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
To shed light on the nature and evolution of structure-function relations in the androgen receptor (AR), we have undertaken a comparative analysis of all available AR and other steroid receptor sequences. We have identified a group of amino acids that "diagnose" the clade of androgen receptors--resi
## BACKGROUND. Endocrine therapy for prostate cancer aims to reduce the levels of circulating androgen or to inhibit androgen action by blocking the androgen receptor in the prostate, or both. Studies in various animal and human prostate cancer models suggested that there may be a downregulation o