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Structure and Expression of the Rat CYP3A1 Gene: Isolation of the Gene (P450/6βB)and Characterization of the Recombinant Protein

✍ Scribed by Kiyoshi Nagata; Makoto Ogino; Miki Shimada; Masaaki Miyata; Frank J. Gonzalez; Yasushi Yamazoe


Book ID
115567452
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
483 KB
Volume
362
Category
Article
ISSN
0003-9861

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✍ Linda Owers Narhi; Long-Ping Wen; Armand J. Fulco 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 648 KB

In two previous reports (Narhi LO, Fulco AJ, J. Biol. Chem. 261: 7160-7169, 1986; Ibid., 262: 6683-6690, 1987) we described the characterization of a catalytically self-sufficient 119,000-dalton P-450 cytochrome that was induced by barbiturates in Bacillus megaterium. In the presence of NADPH and O2