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Structure and Chromosomal Localization of the Human Prostasin (PRSS8) Gene

✍ Scribed by Jack X. Yu; Lee Chao; David C. Ward; Julie Chao

Book ID
115613085
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
226 KB
Volume
32
Category
Article
ISSN
0888-7543

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## Abstract Prostasin (CAP1/PRSS8) is a glycosylphosphatidylinositol‐anchored membrane serine protease believed to be critical for the regulation of epithelial sodium channel (ENaC) activity. Prostasin is synthesized as an inactive zymogen that requires a site‐specific endoproteolytic cleavage to b