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Structure and assembly of pore-forming proteins

✍ Scribed by Ioan Iacovache; Mirko Bischofberger; F Gisou van der Goot


Book ID
113883326
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
340 KB
Volume
20
Category
Article
ISSN
0959-440X

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Pore-Forming Proteins with Built-in Trig
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The self-assembling, pore-forming protein \(\alpha\)-hemolysin is a monomeri:, 293-amino-acid, water-soluble polypeptide that forms heptameric pores of 1 - to 2 -nm internal diameter in lipid bilayers. By genetic engineering and targeted chemical modification, 've have produced \(\alpha\)-hemolysins