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Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy

โœ Scribed by Nigel Unwin


Book ID
117105873
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
312 KB
Volume
555
Category
Article
ISSN
0014-5793

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The interaction of diisopropylfluorophosphate (DFP) with the nicotinic acetylcholine (ACh) receptor of Torpedo electric organ was studied, using [3H]-phencyclidine ([3H]-PCP) as a reporter probe. Phencyclidine binds with different kinetics to resting, activated, and desensitized receptor conformatio