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Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine Cyanobacterium Phormidium sp.

โœ Scribed by Williamson, R. Thomas; Boulanger, Anna; Vulpanovici, Alexandra; Roberts, Mary A.; Gerwick, William H.


Book ID
120328853
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
283 KB
Volume
67
Category
Article
ISSN
0022-3263

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A 14-membered macrolide, koshikalide (1), was isolated from the marine cyanobacterium Lyngbya sp., and its planar structure was elucidated by spectroscopic analysis. The relative stereochemistry of C-11 and C-13 was elucidated by NOESY experiments and by an analysis of 1 H-1 H coupling constants. Ko