✦ LIBER ✦

Isolation and structure of koshikalide, a 14-membered macrolide from the marine cyanobacterium Lyngbya sp.

✍ Scribed by Arihiro Iwasaki; Toshiaki Teruya; Kiyotake Suenaga

Book ID: 104097244
Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 206 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.12.041

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✦ Synopsis

A 14-membered macrolide, koshikalide (1), was isolated from the marine cyanobacterium Lyngbya sp., and its planar structure was elucidated by spectroscopic analysis. The relative stereochemistry of C-11 and C-13 was elucidated by NOESY experiments and by an analysis of 1 H-1 H coupling constants. Koshikalide (1) exhibited weak cytotoxicity against HeLa S 3 cells.

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