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Structure-activity relationships of the δ-opioid-selective agonists, deltorphins

✍ Scribed by Pietro Melchiorri; Lucia Negri; Giuliana Falconieri-Erspamer; Cinzia Severini; Rita Corsi; Marta Soaje; Vittorio Erspamer; Donatella Barra


Book ID
115887029
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
999 KB
Volume
195
Category
Article
ISSN
0014-2999

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Conformation-activity relationships of c
✍ Sylwia Rodziewicz-MotowidŁo; Cezary Czaplewski; Sylwia Łuczak; Jerzy Ciarkowski 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

## Abstract The __N__‐terminal tetrapeptide segments of dermorphin (Tyr–D‐Ala–Phe–Gly–Tyr–Pro–Ser–NH~2~) and deltorphin (Tyr–D‐Ala–Phe–Asp/Glu–Val–Val–Gly–NH~2~) are agonists at the opioid receptors µ and δ, respectively. [D‐Arg^2^, Lys^4^]‐dermorphin‐(1–4) amide (Tyr–D‐Arg–Phe–Lys–NH~2~, DALDA) an