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Structure-activity relationships of neuropeptide FF: role of C-terminal regions

✍ Scribed by Honoré Mazarguil; Christine Gouardères; Jean-André M. Tafani; Delphine Marcus; Masato Kotani; Catherine Mollereau; Michel Roumy; Jean-Marie Zajac

Book ID
117408075
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
168 KB
Volume
22
Category
Article
ISSN
0196-9781

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✍ Jan P. Kochansky; Ashok K. Raina; Thomas G. Kempe 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 58 KB 👁 2 views

A number of analogs of the C-terminal hexapeptide of PBAN were prepared and tested in vivo for pheromonotropic activity in Helicoverpa zea. Peptides prepared with longer-chain omega-aminocarboxylic acids (Tyr-6-aminocaproyl-Leu-NH2 and Tyr-7-aminoheptanoyl-NH2) were active at 25 and 2.5 nmol. Acetyl