omega-Agatoxin IVA, isolated from the venom of funnel web spider Agelenopsis aperta, blocks potently and selectively P-type calcium channels. This toxin, composed of 48 amino acids and containing 8 cysteine residues, was synthesized by the solid-phase procedure. The Cys residues were protected by ac
✦ LIBER ✦
Structure-activity relationships for P-type calcium channel-selective ω-agatoxins
✍ Scribed by Reily, Michael D. ;Holub, Katherine E. ;Gray, William R. ;Norris, Timothy M. ;Adams, Michael E.
- Book ID
- 109965329
- Publisher
- Nature Publishing Group
- Year
- 1994
- Tongue
- English
- Weight
- 433 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1545-9993
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