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SELECTIVITY OF ω-CONOTOXIN GVIA FOR N-TYPE CALCIUM CHANNELS IN RAT ISOLATED SMALL MESENTERIC ARTERIES

✍ Scribed by Sarah L. Whorlow; James A. Angus; Dr Christine E. Wright

Book ID: 108937005
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 630 KB
Volume: 23
Category: Article
ISSN: 0305-1870
DOI: 10.1111/j.1440-1681.1996.tb03056.x

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## Abstract __ω__‐Conotoxin GVIA is a potent, irreversible antagonist of __N__‐type voltage gated Ca^2+^ channels. A radiofluorinated analogue of GVIA could be useful in assessing regional synaptic density of the brain, __in vivo__, using positron emission tomography. __N__‐hydroxy succinimidyl 4‐[