𝔖 Bobbio Scriptorium
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Structure activity relationship of orally active enkephalin analogues as analgesics

✍ Scribed by D. Roemer; J. Pless

Book ID
118938965
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
217 KB
Volume
24
Category
Article
ISSN
0024-3205

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## Abstract The synthesis and biological testing of analogues of Met‐enkephalin, a recently discovered opioid peptide from mammalian brain, are described. Testing involved determination of affinity constants for an opiate receptor site and of analgesic potency in the tail‐flick test in mouse. The e