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Structure-activity relationship for the reactivators of acetylcholinesterase inhibited by nerve agent VX

✍ Scribed by Kamil Kuca; Daniel Jun; Kamil Musilek; Jiri Bajgar

Book ID
119378467
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
77 KB
Volume
164
Category
Article
ISSN
0378-4274

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πŸ“œ SIMILAR VOLUMES

Structureβ€”activity relationships forin v
Structureβ€”activity relationships forin vitrooxime reactivation of chlorpyrifos-inhibited acetylcholinesterase
✍ K. Kuča; V. RačÑkovΓ‘; D. Jun πŸ“‚ Article πŸ“… 2007 πŸ› Versita 🌐 English βš– 187 KB

## Abstract Organophosphorus pesticides parathion, chlorpyrifos, and malathion inhibit the enzyme acetylcholinesterase (AChE; EC 3.1.1.7) via phosphorylation of its active site. AChE reactivators and anticholinergics are compounds used as antidotes in the case of intoxication by these AChE inhibito