𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of acetylcholinesterase by O-(methylcarbamoyl) oximes. Structure-activity relationships

✍ Scribed by Mrlina, Georges; Calmon, Jean Pierre


Book ID
126959444
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
398 KB
Volume
28
Category
Article
ISSN
0021-8561

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Quantitative structure-activity relation
✍ Gialih Lin; Wei-Cheng Liao; Chung-Hwey Chan; Yi-Hian Wu; Hou-Jen Tsai; Chi-Wei H 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

4-Nitrophenyl-N-substituted carbamates (1) are characterized as pseudosubstrate inhibitors of acetylcholinesterase. The first step is formation of the enzyme-inhibitor tetrahedral intermediate with the inhibition constant (K i ), the second step is formation of the carbamyl enzyme with the carbamyla

Structure—activity relationships forin v
✍ K. Kuča; V. Račáková; D. Jun 📂 Article 📅 2007 🏛 Versita 🌐 English ⚖ 187 KB

## Abstract Organophosphorus pesticides parathion, chlorpyrifos, and malathion inhibit the enzyme acetylcholinesterase (AChE; EC 3.1.1.7) via phosphorylation of its active site. AChE reactivators and anticholinergics are compounds used as antidotes in the case of intoxication by these AChE inhibito