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Structural studies on benzothiadiazine derivatives: 3-aminomethyl-1,2,4-benzothiadiazine-1,1-dioxide and 6-aminomethyl-3-methyl-1,2,4-benzothiadiazine-1,1-dioxide hydrochloride monohydrate

✍ Scribed by G. Bombieri; F. Demartin; F. Benetollo; D. Braghiroli; M. Di Bella

Publisher: Springer
Year: 1990
Tongue: English
Weight: 395 KB
Volume: 20
Category: Article
ISSN: 1572-8854
DOI: 10.1007/bf01180113

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## Abstract A new method for the preparation of 4‐substituted 3,4‐dihydro‐1__H__‐2,1,3‐benzothiadiazine 2,2‐dioxides is described. Treatment of __t__‐butyl __N__‐phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u