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Structural studies of the Escherichia coli O90 O-antigen polysaccharide

✍ Scribed by Sanjaya Ratnayake; Göran Widmalm; Andrej Weintraub; Ernesto C. Medina


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
499 KB
Volume
263
Category
Article
ISSN
0008-6215

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✦ Synopsis


The O-specific side-chain of the lipopolysaccharide from Escherichia coli 090 has been investigated using methylation analysis, partial hydrolysis, and NMR spectroscopy as the principal methods. It is concluded that the polysaccharide is composed of tetrasaccharide repeating-units having the following structure. + 4)-(Y-L-Fucp-( 1+2)-P-D-Gab-( 1 + 3)-cx-D-GalpNAc-( 1 + 3)-P-D-GalpNAc-( 1 + 2/3 I OAc The polysaccharide contains approximately one mole of O-acetyl groups per repeating unit, located on the fucose residue.


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