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Structural specificity requirements in the binding of beta lactam antibiotics to human serum albumin

✍ Scribed by Bibiana Nerli; Diana Romanini; Guillermo Picó

Book ID
114009438
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
552 KB
Volume
104
Category
Article
ISSN
0009-2797

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The binding of representative chemical classes of nonsteroidal anti-inflammatory drugs (NSAIDs) to human serum albumin (HSA) was investigated by equilibrium dialysis. Warfarin enantiomers were used as specific markers in displacement studies. Data were analyzed by a computerized nonlinear least squa