The role of albumin conformation in the binding of diazepam to human serum albumin
β Scribed by Jaap Wilting; Betsy J. 'T Hart; Johan J. De Gier
- Book ID
- 113126338
- Publisher
- Elsevier Science
- Year
- 1980
- Weight
- 470 KB
- Volume
- 626
- Category
- Article
- ISSN
- 0005-2795
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Cannabis is the most commonly used illicit drug worldwide. Cannabis users also appear to use other psychoactive drugs more frequently than noncannabis users. Here, Ξ9β tetrahydrocannabinol (THC) and diazepam binding to human serum albumin (HSA) and HSAβheme is reported. THC binds to two
2,3-Benzodiazepines containing a centre of asymmetry at C-5 possess both central and helical chiralities, and the solution of their racemates contains four molecular species. The binding of these compounds to human serum albumin (HSA) was studied by affinity chromatography. The binding strength depe