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Structural separation of different extracellular activities in aminoacyl-tRNA synthetase-interacting multi-functional protein, p43/AIMP1

โœ Scribed by Jung Min Han; Sang Gyu Park; Yeonsook Lee; Sunghoon Kim


Book ID
116292311
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
275 KB
Volume
342
Category
Article
ISSN
0006-291X

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AIMP1 was first found as a factor associated with the aminoacyl-tRNA synthetase (ARS) complex. However, it is also secreted and acts on different target cells such as endothelial cells, macrophages, and fibroblasts as an extracellular regulator, respectively, of angiogenesis, inflammatory responses