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Antitumor activity and pharmacokinetic properties of ARS-interacting multi-functional protein 1 (AIMP1/p43)

โœ Scribed by Jung Min Han; Heejoon Myung; Sunghoon Kim


Book ID
118426799
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
577 KB
Volume
287
Category
Article
ISSN
0304-3835

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AIMP1 was first found as a factor associated with the aminoacyl-tRNA synthetase (ARS) complex. However, it is also secreted and acts on different target cells such as endothelial cells, macrophages, and fibroblasts as an extracellular regulator, respectively, of angiogenesis, inflammatory responses