Competitive Binding Assay of src Homolog
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V.A. Vandernoot; F.A. Fitzpatrick
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Article
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1995
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Elsevier Science
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English
⚖ 600 KB
c-src homology 3 domains (SH3) modulate the formation of a number of protein complexes that are important in cell signaling and cytoskeletal organization. The SH3 domain is recognized by short conserved proline-rich motifs which adopt left-handed polyproline helices on binding. In order to examine m