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Quantitative Structure–Activity Relationship Model for Prediction of Protein–Peptide Interaction Binding Affinities between Human Amphiphysin-1 SH3 Domains and Their Peptide Ligands

✍ Scribed by Yuan Ding; Yong Lin; Mao Shu; Yuanqiang Wang; Li Wang; Xiaoming Cheng; Zhihua Lin


Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
246 KB
Volume
17
Category
Article
ISSN
1573-3149

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## Abstract In this paper, VHESH, which was a novel set of amino acid descriptors including hydrophobic, electronic, steric, and hydrogen bond contribution properties, were proposed to characterize the structures of the decapeptides binding the human amphiphysin‐1 Src homology 3 (SH3) domains, and