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Structural properties of lipid-binding sites in cytoskeletal proteins

✍ Scribed by Verena Niggli


Book ID
114327113
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
277 KB
Volume
26
Category
Article
ISSN
0968-0004

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We have developed a strategy for grafting a protein-protein interface based on the known crystal structure of a native ligand and receptor proteins in a complex. The key interaction residues at the ligand protein binding interface are transferred onto a scaffold protein so that the mutated scaffold