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Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase

✍ Scribed by Chengmin Qian; Xueqi Wang; Karishma Manzur; Sachchidanand; Amjad Farooq; Lei Zeng; Rong Wang; Ming-Ming Zhou


Book ID
116662938
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
819 KB
Volume
359
Category
Article
ISSN
0022-2836

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## Abstract Histone lysine methylation is a dynamic chromatin modification that plays key regulatory roles in gene expression and other genomic functions. Methylation of Lys9 in histone H3 (H3K9) is a prominent modification that has been implicated in diverse processes, including transcriptional si