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Purification and Functional Characterization of a Histone H3-Lysine 4-Specific Methyltransferase

✍ Scribed by Hengbin Wang; Ru Cao; Li Xia; Hediye Erdjument-Bromage; Christoph Borchers; Paul Tempst; Yi Zhang

Book ID
117736676
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
637 KB
Volume
8
Category
Article
ISSN
1097-2765

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## Abstract Histone lysine methylation is a dynamic chromatin modification that plays key regulatory roles in gene expression and other genomic functions. Methylation of Lys9 in histone H3 (H3K9) is a prominent modification that has been implicated in diverse processes, including transcriptional si