The metabolism of the anti-inflammatory drug Celecoxib in rabbits was characterized using liquid chromatography (LC)/tandem mass spectrometry (MS/MS) with precursor ion and constant neutral loss scans followed by product ion scans. After separation by on-line liquid chromatography, the crude urine s
Structural elucidation of in vitro metabolites of emodin by liquid chromatography–tandem mass spectrometry
✍ Scribed by Rui Song; Fengguo Xu; Zunjian Zhang; Ying Liu; Haijuan Dong; Yuan Tian
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 241 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.1050
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
This paper presents liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS) approaches for the rapid characterization of three urinary isomeric metabolites and their two precursor metabolites of SYN-2836, a novel antifungal agent, in dogs adminis
Erythromycin A (EryA) was studied by electrospray ionisation tandem mass spectrometry (ESI-MS/MS) with the aim of developing a methodology for the structural elucidation of novel erythromycins developed by biological synthetic methods. Skimmer dissociation along with sequential mass spectrometry stu
A rapid and systematic strategy for the identification of drug metabolites in biological matrices based on liquid chromatography -tandem mass spectrometry (LC/MS/MS) techniques was utilized for the identification of drug metabolites of the HIV protease inhibitor Indinavir. This strategy integrates i